Krang is often a prominent villain in video games based on the original cartoon - he is usually the penultimate boss, but on occasion he takes the role as final boss, and sometimes shows up as an additional challenge earlier in the game.
Krang first shows up in the Technodrome stage of the original arcade game, serving as a boss following Traag and before Shredder. He fights in his android body, using kicks, eyebeams, and rocket fists. Occasionally, he will stop and flex; this is normally done after he scores a hit, but not always. This gives players a free chance at attacking Krang. After beating the android, Krang floats on a disc momentarily, saying "I'm invincible" before rocketing offscreen.
Krang, again in his android, serves as the final boss in Teenage Mutant Ninja Turtles: Fall of the Foot Clan. His only attack here is an awkward jump kick. Upon defeat, he will fade back into the portal from whence he came.
Krang in his android body return as a penultimate boss in Teenage Mutant Ninja Turtles III: The Manhattan Project. He retains the rocket fist from the arcade game, but also adds an electric field and chest missiles to his armory. At about half health, he splits in two, with his legs running around in an effort to kick the Turtles, while the rest of his body floats around firing eyebeams and trying to crush them with his hammer arm. When he gets down to 1/4 health, his sections rejoin, repeating the tactics he used before.
He gets double boss duty in Teenage Mutant Ninja Turtles II: Back from the Sewers, appearing first in a giant, modified version of his "bubble walker" at the climax of stage 3. Here, Krang fires rays from the front of his walker, missiles from the back, and rockets around the sky in an attempt to drop down and crush the Turtles. As the final boss in his android body, Krang only will stomp the ground or leap up and stomp on his descent.
Krang's theft of the Statue of Liberty is the focal point of the story of Teenage Mutant Ninja Turtles: Turtles in Time. In the first stage (Big Apple, 3 AM), his oversized android will attempt to fry the Turtles with its lasers. The android returns back in its (relative) normal size at the end of Neon Night-Riders. Krang, here, as a dashing kick, chest missiles, a hammer punch, and fires some sort of explosives from the android's mouth. He returns in Starbase: Where No Turtle Has Gone Before in an awkward flying saucer, attempting to trap Turtles in bubbles, and dropping Flippers. In the arcade version, Krang seems to have two voices, both uncredited. His voice in Big Apple, 3 AM is an unemotional male voice that intones "Prepare to die," while later stages give him a gurgling voice similar to his cartoon incarnation. Wayne Grayson voices Krang in the Re-Shelled version, using a different voice than the Utrom Krang in the 2003 series.
Teenage Mutant Ninja Turtles: The Hyperstone Heist sees Krang returning as the fight directly prior to Super Shredder, fighting much like his "Super Krang" android incarnation in Turtles in Time.
Krang is also the penultimate boss before Karai in the Genesis version of Teenage Mutant Ninja Turtles: Tournament Fighters. His android's fists are tethered to chains this time, allowing him to fire them off and retract them; his feet are also tethered in this way. Krang also can fire missiles from his elbows and shins. Krang's Android is typically unplayable, but can be made playable with a cheat device or trainer program.