In Archie Comics' Teenage Mutant Ninja Turtles Adventures, Michaelangelo is initially presented very similarly to his 1987 cartoon portrayal-understandable considering the comic started as an adaption of the popular animated series. As the series progressed, Archie's Michaelangelo was presented as more mature than the cartoon version. This version developed also an interest in poetry. During a battle, he was temporarily blinded and later captured by the U.S. Military, whereupon he was interrogated and tortured. He was eventually rescued by his family and saved the life of the man who tortured him.
One of his many skills in the Archie comics was also to communicate with animals. In a storyline set in the future, Michaelangelo is shown to have become an artist whose main job is running an orphanage.